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Having achy, painful joints isn't just a physical woe: Coupled with depression, it could also degrade an older person's brain function over time.

That's the conclusion of a study of almost 5,000 older Britons tracked for 12 years. People who had both chronic joint pain and depression tended to perform worse on cognitive tests, especially tests focused on memory skills.

“Both p...

The GLP-1 drug semaglutide can help obese people manage debilitating knee arthritis, a new trial has found.

People who received weekly injections of semaglutide -- the active agent in the diabetes drug Ozempic and the weight-loss medication Wegovy -- had a nearly 14% decrease in their body weight after 68 weeks, compared with 3% of people given a placebo, results showed. The trial was fun...

Gene therapy could help obese kids avoid health problems associated with excess weight, including arthritis, a new, preliminary study in mice suggests.

The gene therapy prompts cells to convert inflammation-causing omega-6 fatty acids into beneficial omega-3 fatty acids, researchers reported Oct...

Doctors sometimes turn to antidepressants as a means of easing older people's physical pain, but a new expert review finds there's little evidence to support the practice.

Antidepressants may even come with hazards for seniors who don't need them, said researchers from the University of Sydney in Australia.

"Harms of antidepressant use in older people are well documented," said stud...

An arthritis sufferer’s joints start to get ornery when the weather turns colder, getting stiff and achy as the mercury drops.

Cold weather doesn’t cause arthritis, but it can make it worse, experts say.

"Our joints operate best in temperate weather," said Dr. Mariko Ishimori, interim director at the Ceda...

The knee develops differently in men and women, with sex-specific distinctions in the joint appearing as early as childhood, a new study finds.

Taking these differences into account among girls could help prevent knee arthritis for women later in life, researchers say.

Gender-based differences in knee cartilage and ligaments develop prior to puberty and can’t be explained by ...

Brent Ruch, a collegiate basketball center, opted to have his left knee replaced at age 35 after struggling with pain for years.

“Walking with a limp and living with a consistent aching pain was physically and emotionally difficult.  I didn’t want to live like that,” said Ruch, who lives in a suburb of Chicago.

When his doctor told him he’d be pla...

Eating fish while pregnant doesn't appear to increase a child's later risk of juvenile arthritis, particularly if the fish is oily like salmon, trout or sardines, new research shows.

"We cannot caution pregnant women against consuming fish solely based on this study in regards to [juvenile arthritis] risk, especially considering other research highlighting the positive impacts of a marine...

People who regularly ride bikes throughout their life are less likely to develop knee arthritis, a new study suggests.

Bicyclists are 17% less likely to have knee pain and 21% less likely to have symptoms of knee arthritis, compared to people who've never biked, researchers discovered.

It also appears that people who've biked all their lives have a lower risk of knee arthritis than ...

Robot-assisted total knee replacements tend to have better outcomes on average, a new study reports.

Unfortunately, there's a downside"having a surgical robot assist a human surgeon can make the procedure much more costly.

Patients who had a robot-assisted knee replacement stayed i...

A blood test could help doctors spot the signs of knee osteoarthritis at least eight years before it shows up on X-rays, a new study claims.

After analyzing the blood of 200 white British women, half diagnosed with knee osteoarthritis and half without, researchers discovered a small number of biomarkers distinguished the women with osteoarthritis from those without it.

"We found we ...

Early-onset arthritis may hit as many as one in every four young people who undergo anterior cruciate ligament (ACL) reconstruction surgeries, new research warns.

The arthritic pain emerges within 6 to 12 months post-surgery, according to Michigan State University (MSU) researchers.

Many of these cases occur in people under 40 and go unrecognized and untreated.

"We're trying...

Once considered harmless by doctors, calcium crystal deposits in the knee joint actually can contribute to worsening arthritis, a new study warns.

CT scans have revealed that calcium crystals in the knee can promote joint damage, wearing away the cartilage that keeps bones from rubbing together, researchers reported recently in the journal